A specialised load transporter carrying an Airbus A321 aircraft fuselage, will be escorted by Wiltshire Police on Sunday, March 9.
Due to the size of this transporter it will be slow moving and could create congestion.
Wiltshire Police say that wherever possible disruption will be kept to a minimum but hauliers and motorists are asked to be patient if they come across this load.
The transporter and its load will measure 6.10 metres (20ft) wide, 4.9 m (16ft) high with an overall length of 46m (151 ft) and gross weight of 58 tonnes.
The abnormal load will be travelling from MOD St Athan, near Barry, South Wales, to Cotswold Airport, Kemble, near Cirencester, Gloucestershire.
Anyone travelling over this period to catch a flight or meet appointments should allow sufficient additional time.
While on the A419 it will take up both northbound carriageways and police are asking other motorists to be patient.
Regular updates and travel information in respect of this abnormal load will be passed from the police control room at Devizes to help motorists plan their journey.
The journey will begin in Wiltshire at about 1.30pm from M4 Junction 18, where the load will be transported in convoy.
It is due to depart from M4 junction 18 to junction 15 before travelling North on the A419 towards Cirencester, then onto the A429 to arrive at Kemble.
Police escorting resources are being provided by volunteer police officers on rest days, paid for by the haulier at no cost to the public.
The load was due to move on February 9 but this was cancelled due to extremely windy weather.